MBPhD projects available

Project 1: Investigating the roles of Polε in genome stability and sensitization to ATR and PARP inhibitors

Primary supervisor: Roberto Bellelli, Queen Mary University of London Co-supervisors: David Michod, UCL

Project 2: Unravelling c-Met endosomal signalling to improve breast cancer therapy

Primary supervisor: Stephanie Kermorgant, Queen Mary University of London Co-supervisor: J Louise Jones, Queen Mary University of London

Project 3: Unravelling the Role of ZEB1 in Chronic Lymphocytic Leukaemia Progression: Pathways to Novel Therapeutic Insights

Primary supervisor: Sergey Krysov, Queen Mary University of London Secondary supervisor: Maxim Freydin, Queen Mary University of London

Project 4: Deciphering LIMD1’s Impact on Lung Cancer Progression and Therapeutic Response Using Novel Conditional Mouse Models

Primary supervisor: Tyson Sharp, Queen Mary University of London Secondary supervisor: Adam Januszewski, Queen Mary University of London,  Nicholas McGranahan, UCL

Project 1: ecDNA in circulating tumour DNA

Primary supervisor: Mariam Jamal-Hanjani, UCL Secondary supervisor: Nnenna Kanu, UCL

Project 2: Modelling the evolution and ecology of cancer resistance to develop new proton radiobiology insights

Primary supervisor: Maria Secrier, UCL Secondary supervisor: Maria Hawkins, UCL

Project 3: Leveraging the role of oncogenes and tumour suppressors genes in 1p-/1q+ myeloma

Primary supervisor: Kwee Yong, UCL Advisor: Dinis Calado, Francis Crick Institute

Project 1: Understanding how initiating genetic mutations permit the emergence of full-blown cancer using IPSC models of childhood leukaemia

Primary supervisor: Tariq Enver, UCL Secondary supervisor: Charles Swanton, Francis Crick Institute/ UCL

Project 2: Germline predisposition to gene-specific somatic mutagenesis

Primary supervisor: Veronica Kinsler, Francis Crick Institute/ UCL

Project 3: Identifying the injury signals that drive early glioblastoma growth

Primary supervisor: Simona Parrinello, UCL Secondary supervisor: Samuel Marguerat, UCL